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Metabolism/Transport effects substrate: None known.
Avoid concomitant use: Avoid concomitant use of Pregabalin with any of the following: Azelastine (Nasal); Bromperidol; Orphenadrine; Oxomemazine; Paraldehyde; Thalidomide.
Increased effect/toxicity: Pregabalin may increase the levels/effects of: Alcohol (Ethyl); Azelastine (Nasal); Blonanserin; Buprenorphine; CNS Depressants; Flunitrazepam; Hydrocodone; Methotrimeprazine; Metyrosine; Mirtazapine; Opioid Analgesics; Orphenadrine; Oxycodone; Paraldehyde; Piribedil; Pramipexole; Ropinirole; Rotigotine; Selective Serotonin Reuptake Inhibitors; Suvorexant; Thalidomide; Thiazolidinediones; Zolpidem.
The levels/effects of Pregabalin may be increased by: Alizapride; Angiotensin-Converting Enzyme Inhibitors; Brimonidine (Topical); Bromopride; Bromperidol; Cannabidiol; Cannabis; Chlormethiazole; Chlorphenesin Carbamate; Dimethindene (Topical); Doxylamine; Dronabinol; Droperidol; Hydroxyzine; Kava Kava; Lofexidine; Magnesium Sulfate; Methotrimeprazine; Minocycline; Nabilone; Oxomemazine; Perampanel; Rufinamide; Sodium Oxybate; Tapentadol; Tetrahydrocannabinol; Tetrahydrocannabinol and Cannabidiol; Trimeprazine.
Decreased effect: The levels/effects of Pregabalin may be decreased by: Mefloquine; Mianserin; Orlistat.
